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Add water to peptide vial slowly Insert the needle into the AOD-9604 vial at an angle

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Important Safety Information Do not use AOD-9604 if you: Have active cancer or malignancy (use only under medical supervision with appropriate monitoring) Are pregnant or breastfeeding (safety data lacking in these populations) Have known allergy to growth hormone fragments or peptide compounds Have severe uncontrolled metabolic or cardiovascular disease without medical supervision Common side effects may include: Injection site reactions (mild redness, swelling, or tenderness), occasional mild headaches during initial use, and transient lightheadedness

Lessons for Peptide Drug Development AOD-9604 highlights how promising biochemical logic can falter in translation from bench to bedside